Kaltura Share to Google Classroom Located along the South Carolina - North Carolina border in Pickens County and towering over 3,500 feet, Sassafras Mountain is the highest point in the state of South Carolina. Grades: 3 4 5 6 7 8 9 10 11 12 Subjects: Science Collection: Explore South CarolinaPlaces to Visit in S.C.Native American HeritageCherokeesSouth Carolina CountiesPickens Series: